The Big "M" Casino sails days a year from Little River, SC. Check out our pricing and cruise schedules for both gambling ships here. Book your tickets online for Big M Casino, Little River: See reviews, articles, Big M Casino Cruise Ship II in Myrtle Beach . Little River, South Carolina. () · Waterfront Ave Little River, SC Yes you are trapped on the boat for close to 6 hours and they allow smoking on the boat. If the.